CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 20 target
Drug / intervention
Tetrahydrocannabinol (10 mg) +3 moredrug
Likely dose
Tetrahydrocannabinol (10 mg)from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06967051
NCT06967051N/ARecruitingUpdate OverdueUpdated 11mo ago · Completion was 11mo ago
Enrollment Stalled
Update Overdue
CompareCT.gov

An Open Label Pilot Study Evaluating the Efficacy of a Smart Phone-based Test on Measuring Pupillary Light Reflex Alterations Following Cannabis Use Healthy in Adults

Sobereye Inc.·interventional·Posted May 13, 2025·Updated Jul 17, 2025

In Brief

A clinical study evaluating Tetrahydrocannabinol (10 mg), Tetrahydrocannabinol (25 mg), and 2 other interventions for Cannabis Intoxication and Drug Effects. Currently recruiting, targeting 20 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

The goal of this open label study is to evaluate the efficacy of smart phone-based test (SOBEREYE OPTOVERA) on measuring pupillary light reflex (PLR) alterations following cannabis use healthy in adults. The main question it aims to answer is: Can SOBEREYE OPTOVERA detect PLR alterations following cannabis consumption in healthy adults, in comparison to a pupillometer? Participants will be given two 5 mg capsules to be ingested for the 10 mg THC dose or five 5 mg capsules to be ingested for the 25 mg THC. Participants will be asked to complete PLR tests throughout the study day.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCannabis Intoxication, Drug Effects
CountriesCanada
CollaboratorsKGK Science Inc.

Timeline

N/ARecruitingOverdue
2026
First PostedMay 13, 2025
Enrollment StartMay 22, 2025
Primary CompletionAug 1, 2025
TodayJul 1, 2026
Enrollment to primary: 2 monthsPosted 1.1 years ago

Interventions

Tetrahydrocannabinol (10 mg)drug

10 mg of Tetrahydrocannabinol (THC) provided as a softgel capsule

Tetrahydrocannabinol (25 mg)drug

25 mg of THC provided as a softgel capsule.

Pupillary Light Reflex (PLR) Testother

SOBEREYE OPTOVERA is a portable, non-invasive test that measures the Pupillary Light Reflex (PLR)

Pupillometerother

NeuroLight is an automated pupillometer that generates a flash of light and measures the photomotor reflex very accurately.