CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 70 target
Drug / intervention
Spray of spirulina derivatives +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07040969
NCT07040969Phase 2ActiveMonitorUpdated 2mo ago · Completion was 5mo ago
Slow Enrollment

Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors: A Randomized Controlled Trial

West China Hospital·interventional·Posted Jun 27, 2025·Updated Apr 7, 2026

In Brief

A Phase 2 clinical trial evaluating Spray of spirulina derivatives, Spray of placebo, and 1 other intervention for Radiation-induced Oral Mucositis. Active but no longer recruiting, targeting 70 participants across 1 site.

Signals

Enrolling slower than its timeline implies

Detailed Summary

To evaluate the efficacy and safety of Spirulina-Derived Product for prevention and treatment of oral mucositis in patients undergoing radiotherapy for malignant head and neck tumors.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2ActiveOverdue
2026
First PostedJun 27, 2025
Enrollment StartJun 27, 2025
Primary CompletionJan 15, 2026
Study CompletionApr 30, 2026
TodayJul 1, 2026
Enrollment to primary: 7 monthsPosted 1.0 years ago

Interventions

Spray of spirulina derivativesdrug

An oral spray formulated with purified spirulina-derived exosomes.

Spray of placebodrug

The placebo oral spray will be formulated with inactive ingredients matched in appearance and flavor profile to the active spirulina-derived product.

Radiotherapyradiation

One of the inclusion criteria for the study was that patients with squamous carcinoma of the head and neck (including nasopharyngeal carcinoma) needed to receive either radiotherapy alone or simultaneous radiotherapy and chemotherapy.