CI

At a glance

ClinicalIndex Comparison Record
Phase 1Not Yet Recruiting· 132 target
Drug / intervention
Low dose of Megestrol Acetate Oral Suspension combined with standard therapy +3 moredrug
Likely dose
Low dose of Megestrol Acetate Oral Suspension combined with standard therapy 312.5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07130617
NCT07130617Phase 1Not Yet Recruiting

A Phase Ib, Multicenter, Randomized, Double-blind, Placebo-controlled Parallel Group Clinical Study Evaluating the Efficacy and Safety of Megestrol Acetate Oral Suspension in Preventing Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy

Changchun GeneScience Pharmaceutical Co., Ltd.·interventional·Posted Aug 19, 2025·Updated Aug 19, 2025

In Brief

A Phase 1 clinical trial evaluating Low dose of Megestrol Acetate Oral Suspension combined with standard therapy, Medium dose of Megestrol Acetate Oral Suspension combined with standard therapy, and 2 other interventions for Efficacy and 3 related conditions. Not yet recruiting, targeting 132 participants across 1 site.

Detailed Summary

To evaluate the efficacy of Megestrol Acetate Oral Suspension in Preventing Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy in Malignant Solid Tumor Patients

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 1Not Yet Recruiting
2026
First PostedAug 19, 2025
Enrollment StartSep 29, 2025
Primary CompletionJul 31, 2026
TodayJul 1, 2026
Enrollment to primary: 10 monthsPosted 10 months agoPrimary completion in 1 month

Interventions

Low dose of Megestrol Acetate Oral Suspension combined with standard therapydrug

A single dose of 312.5 mg/day, administered once daily (QD) for 7 consecutive days.

Medium dose of Megestrol Acetate Oral Suspension combined with standard therapydrug

A single dose of 625 mg/day, administered once daily (QD) for 7 consecutive days.

High dose of Megestrol Acetate Oral Suspension combined with standard therapydrug

A single dose of 937.5 mg/day, administered once daily (QD) for 7 consecutive days.

Megestrol Acetate Oral Suspension Placebo combined with standard therapydrug

A single dose of 5 mL/day, administered once daily (QD) for 7 consecutive days.