CI

At a glance

ClinicalIndex Comparison Record
Phase 3Recruiting· 420 target
Drug / intervention
ZG006 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07189455
NCT07189455Phase 3RecruitingOn TrackUpdated 5mo ago

A Multicenter, Randomized, Controlled, Open-Label Phase III Study Evaluating the Efficacy and Safety of ZG006 for Injection Compared With Investigator-Selected Chemotherapy in Participants With Relapsed Small Cell Lung Cancer

Suzhou Zelgen Biopharmaceuticals Co.,Ltd·interventional·Posted Sep 24, 2025·Updated Jan 5, 2026

In Brief

A Phase 3 clinical trial evaluating ZG006 and Topotecan for Small-cell Lung Cancer. Currently recruiting, targeting 420 participants across 1 site.

Detailed Summary

The main objective is to compare ZG006 with Investigator-Selected Chemotherapy on prolonging overall survival (OS).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 3Recruiting
2026202720282029
First PostedSep 24, 2025
Enrollment StartDec 12, 2025
Primary CompletionOct 1, 2028
Study CompletionDec 1, 2028
TodayJul 1, 2026
Enrollment to primary: 2.8 yearsPosted 9 months agoPrimary completion in 2.3 years

Interventions

ZG006drug

ZG006 will be administered as an intravenous (IV) infusion.

Topotecandrug

Topotecan will be administered per local standard of care