CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 90 target
Drug / intervention
Open Pancreaticoduodenectomy +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07328607
NCT07328607N/ARecruitingOn TrackUpdated 5mo ago
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Open Versus Laparoscopic Pancreaticoduodenectomy: A Randomized Controlled Trial

Minia University·interventional·Posted Jan 9, 2026·Updated Jan 21, 2026

In Brief

A clinical study evaluating Open Pancreaticoduodenectomy and Laparoscopic Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma and 4 related conditions. Currently recruiting, targeting 90 participants across 1 site.

Detailed Summary

This is a monocentric, prospective, randomized controlled trial comparing the safety and efficacy of laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD). The study aims to determine the morbimortality of the laparoscopic approach compared to the gold standard open approach in adult patients with pancreatic or periampullary lesions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPancreatic Ductal Adenocarcinoma, Ampullary Carcinoma, Distal Cholangiocarcinoma, Duodenal Adenocarcinoma, Pancreatic Neuroendocrine Tumor
CountriesEgypt
Collaborators--

Timeline

N/ARecruiting
202620272028
First PostedJan 9, 2026
Enrollment StartJan 17, 2026
Primary CompletionJan 15, 2028
Study CompletionApr 15, 2028
TodayJul 1, 2026
Enrollment to primary: 2.0 yearsPosted 6 months agoPrimary completion in 1.5 years

Interventions

Open Pancreaticoduodenectomyprocedure

Open Pancreaticoduodenectomy with lymphadenectomy and reconstruction via open technique.

Laparoscopic Pancreaticoduodenectomyprocedure

Minimally invasive Whipple procedure using 6 trocars, with specimen extraction via Pfannenstiel incision.